PZ0377

PF-05236216 hydrochloride

≥98% (HPLC)

• 同義詞: 4-[3-(4-Fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-6,7-dihydro-6-methyl-5H-pyrrolo[3,4-b]pyridin-5-one hydrochloride, PF-5236216 hydrochloride
• 經驗公式（希爾表示法）: C₁₈H₁₅FN₄O · HCl
• CAS號碼: 1383376-93-9
• 分子量：: 358.80
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: CN1C=C(C2=CC=NC(CN3C)=C2C3=O)C(C4=CC=C(F)C=C4)=N1.Cl
• InChI: 1S/C18H15FN4O.ClH/c1-22-10-15-16(18(22)24)13(7-8-20-15)14-9-23(2)21-17(14)11-3-5-12(19)6-4-11;/h3-9H,10H2,1-2H3;1H
• InChI 密鑰: CLDJMFXSCFWXDI-UHFFFAOYSA-N

描述

生化／生理作用

PF-05236216 is a brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε) that modulates circadian rhythms in mice.

brain penetrant, potent and selective inhibitor of casein kinase 1 delta/epsilon (CK1δ/ε)

法律資訊

Sold for research purposes under agreement from Pfizer Inc.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable