PZ0284

PF-04753299

≥98%

• 同義詞: α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299
• 經驗公式（希爾表示法）: C₁₈H₂₁NO₄S
• CAS號碼: 1289620-49-0
• 分子量：: 347.43
• MDL號碼: MFCD22683864
• 分類程式碼代碼: 51111800
• PubChem物質ID: 329823811
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98%
• 形狀: powder
• 顏色: white to light brown
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2
• InChI: 1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1
• InChI 密鑰: GDYIQUFNICPYHF-GOSISDBHSA-N

描述

生化／生理作用

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable