PRS4379
Anti-Nhe-1 (ab2) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
同義詞:
Anti-Na+/H+ antiporter, Anti-SLC9A1, Anti-Sodium-hydrogen exchanger 1, Anti-Solute carrier family 9 (sodium/hydrogen exchanger), member 1, Anti-Solute carrier family 9 member 1
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About This Item
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
mouse, human, rat
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... SLC9A1(6548)
一般說明
SLC9A1 (solute carrier family 9 member A1)/Na+/H+ exchanger 1 (NHE1), a plasma membrane transporter, is mapped to human chromosome 1p36. It belongs to the NHE family. NHE1 is abundantly expressed in all organisms.
免疫原
a 17 amino acid peptide near the center of the human Nhe-1.
應用
Anti-Nhe-1 (ab2) antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
生化/生理作用
Na+/H+ exchanger 1 (NHE1) modulates intracellular pH by exchanging a proton for an extracellular sodium ion and affects cell growth, proliferation, migration and apoptosis. It plays a major role in cancers including breast cancer, hepatocellular carcinoma, colon cancer, pancreatic ductal adenocarcinoma, prostate cancer, cervical cancer and neuroblastoma.
聯結
The action of this antibody can be blocked using blocking peptide SBP4379.
外觀
Solution in phosphate buffered saline containing 0.02% sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Effects and mechanism of Xin Mai Jia in a rabbit model of atherosclerosis.
Experimental and Therapeutic Medicine, 10(5), 1627-1634 (2015)
Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.
Oncotarget, 8(2), 2209-2209 (2017)
Journal of the American College of Cardiology, 38(4), 1175-1180 (2001-10-05)
The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and
Experimental and therapeutic medicine, 10(5), 1627-1634 (2015-12-08)
The aim of this study was to investigate the protective effects of Xin Mai Jia (XMJ) on atherosclerosis (AS) in rabbits and to explore the underlying mechanisms in order to provide experimental evidence for the clinical application of XMJ. An
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