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Key Documents

PRS4379

Sigma-Aldrich

Anti-Nhe-1 (ab2) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Na+/H+ antiporter, Anti-SLC9A1, Anti-Sodium-hydrogen exchanger 1, Anti-Solute carrier family 9 (sodium/hydrogen exchanger), member 1, Anti-Solute carrier family 9 member 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.43

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, human, rat

技術

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SLC9A1(6548)

相關類別

一般說明

SLC9A1 (solute carrier family 9 member A1)/Na+/H+ exchanger 1 (NHE1), a plasma membrane transporter, is mapped to human chromosome 1p36. It belongs to the NHE family. NHE1 is abundantly expressed in all organisms.

免疫原

a 17 amino acid peptide near the center of the human Nhe-1.

應用

Anti-Nhe-1 (ab2) antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

生化/生理作用

Na+/H+ exchanger 1 (NHE1) modulates intracellular pH by exchanging a proton for an extracellular sodium ion and affects cell growth, proliferation, migration and apoptosis. It plays a major role in cancers including breast cancer, hepatocellular carcinoma, colon cancer, pancreatic ductal adenocarcinoma, prostate cancer, cervical cancer and neuroblastoma.

聯結

The action of this antibody can be blocked using blocking peptide SBP4379.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Effects and mechanism of Xin Mai Jia in a rabbit model of atherosclerosis.
Zhao FR, et al.
Experimental and Therapeutic Medicine, 10(5), 1627-1634 (2015)
Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.
Ariyoshi Y, et al.
Oncotarget, 8(2), 2209-2209 (2017)
D S Lim et al.
Journal of the American College of Cardiology, 38(4), 1175-1180 (2001-10-05)
The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and
Fan-Rong Zhao et al.
Experimental and therapeutic medicine, 10(5), 1627-1634 (2015-12-08)
The aim of this study was to investigate the protective effects of Xin Mai Jia (XMJ) on atherosclerosis (AS) in rabbits and to explore the underlying mechanisms in order to provide experimental evidence for the clinical application of XMJ. An

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