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PRS4243

Sigma-Aldrich

Anti-IFN-β antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Interferon, beta 1, fibroblast

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human, mouse

技術

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... IFNB1(3456)

一般說明

Interferon-β (IFN-β) is a cytokine that belongs to type I interferons. The IFN-β gene is mapped on the human chromosome at 9p21.3.

免疫原

a 17 amino acid peptide from near the center of human IFN-b.

生化/生理作用

Interferon-β (IFN-β) plays a major role in antibacterial and antiviral defense. It is also involved in apoptosis, cell growth, and autoimmune disorders. It binds to multimeric cell receptors and successful binding results in a cascade of intracellular events.

聯結

The action of this antibody can be blocked using blocking peptide SBP4243.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Amber Kaplan et al.
Journal of immunology (Baltimore, Md. : 1950), 198(10), 4036-4045 (2017-04-16)
Type I IFNs are a cytokine family essential for antiviral defense. More recently, type I IFNs were shown to be important during bacterial infections. In this article, we show that, in addition to known cytokine functions, IFN-β is antimicrobial. Parts

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