生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
predicted mol wt 16 kDa
物種活性
mouse, human
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... NRN1(51299)
一般說明
Neuritin (NRN1) is a candidate plasticity associated gene, that is a member of the neurotrophic factor family. It is also known as CPG15. It is expressed in the liver, heart, lungs, skeletal muscle and other normal organs along with the nervous system. It is also expressed in gastric cancer tissues. It is mapped to chromosome 6p24-p2.
免疫原
a 20 amino acid peptide from near the center of human neuritin.
應用
Anti-Neuritin has been used in immunohistochemistry and western blotting.
生化/生理作用
In gastric cancer treatment, neuritin (NRN1) serves as a potential target. It also participates in the pathogenesis of tumors. It plays a major role in the nervous system and on the migration, senescence, proliferation, and viability of stem cells.
聯結
The action of this antibody can be blocked using blocking peptide SBP4101.
外觀
Solution in phosphate buffered saline containing 0.02% sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Frontiers in oncology, 11, 758503-758503 (2021-11-23)
Acquired therapeutic resistance and metastasis/recurrence remain significant challenge in advance renal cell carcinoma (RCC), thus the establishment of patient-derived cancer models may provide a clue to assess the problem. We recently characterized that neuritogenesis-related protein neuritin 1 (NRN1) functions as
Effects of neuritin on the migration, senescence and proliferation of human bone marrow mesenchymal stem cells
Cellular & Molecular Biology Letters, 20(3), 466-474 (2015)
Overexpression of neuritin in gastric cancer
Oncology Letters, 10(6), 3832-3836 (2015)
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 153B(2), 428-437 (2010)
Oncology letters, 10(6), 3832-3836 (2016-01-21)
The aim of the present study was to investigate the expression of neuritin in gastric cancer tissues, in order to explore the association between the expression of neuritin and the occurrence and development of gastric cancer. Tissue specimens were collected
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