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Merck
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重要文件

PLA0215

Sigma-Aldrich

Rabbit anti-NF-kappaB2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

同義詞:

CVID10, DNA-binding factor KBF2, H2TF1, LYT-10, LYT10, NF-kB2, NFKB, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, lymphocyte translocation chromosome 10 protein, nuclear factor Kappa-B, nuclear factor NF-kappa-B p52 subunit, nuclear factor of Kappa light chain gene enhancer in B cells 2, nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), oncogene Lyt-10, p100, p105, p49/p100, p52, p52/p100 subunit, subunit 2, transcription factor NFKB2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
物種活性:
mouse, human
application:
IP
WB
技術:
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000
citations:
2

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

等級

Powered by Bethyl Laboratories, Inc.

物種活性

mouse, human

技術

immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000

登錄號

NP_001070962.1

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

免疫原

The epitope recognized by PLA0215 maps to a region between residue 810 and 860 of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) using the numbering given in entry NP_001070962.1 (GeneID 4791).

外觀

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他說明

The NFKB2 gene encodes a 100 kDa protein that can undergo co-translational processing to also yield a 52 kDa protein. The 52 kDa protein is also known as NF-kappa B2/p52 and is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The 100 kDa product is also known as p100 or I kappa B delta. P100/I kappa B delta has been shown to function as an inhibitor protein that interacts with NF-kappa B and inhibit its DNA binding activity. P100/I kappa B delta is a member of the I kappa B family of proteins which includes I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa B1/p105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. The classical description of the NF-kappa B transcription factor is a transcription factor that reprograms gene expression of the immune system in response to injury, infection, and stress.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Chang Jiang et al.
Cell reports, 28(5), 1307-1322 (2019-08-01)
CD40 has major roles in B cell development, activation, and germinal center responses. CD40 hypoactivity causes immunodeficiency whereas its overexpression causes autoimmunity and lymphomagenesis. To systematically identify B cell autonomous CD40 regulators, we use CRISPR/Cas9 genome-scale screens in Daudi B
Haihui Lu et al.
Nature cell biology, 16(11), 1105-1117 (2014-10-01)
The cell-biological program termed the epithelial-mesenchymal transition (EMT) confers on cancer cells mesenchymal traits and an ability to enter the cancer stem cell (CSC) state. However, the interactions between CSCs and their surrounding microenvironment are poorly understood. Here we show

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