PLA0173

Rabbit anti-CDC20 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• 同義詞: CDC20 (cell division cycle 20, CDC20 cell division cycle 20 homolog, CDC20 cell division cycle 20 homolog (S. cerevisiae), CDC20A, S. cerevisiae, bA276H19.3, cell division cycle 20 homolog, cell division cycle 20 homolog (S. cerevisiae), homolog), p55CDC
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity purified immunoglobulin
• 抗體產品種類: primary antibodies
• 等級: Powered by Bethyl Laboratories, Inc.
• 物種活性: human, mouse
• 技術: immunohistochemistry: 1:500- 1:2,000; immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000- 1:10,000
• 登錄號: NP_001246.2
• UniProt登錄號: Q12834
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: rabbit ... CDC20(991)

描述

免疫原

The epitope recognized by PLA0173 maps to a region between residue 449 and 499 of human cell division cycle 20 using the numbering given in entry NP_001246.2 (GeneID 991).

外觀

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

其他說明

CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable