P9109

Monoclonal Anti-Protein Tyrosine Phosphatase PEST antibody produced in mouse

clone AG25, purified immunoglobulin

• 同義詞: Anti-PTP PEST
• MDL號碼: MFCD02688691
• 分類程式碼代碼: 12352203
• NACRES: NA.44
• 共軛: unconjugated
• application: IP; WB
• 無性繁殖: AG25, monoclonal
• 物種活性: mouse, human, bovine, rat
• citations: 2
• 技術: immunoprecipitation (IP): suitable; western blot: suitable

屬性

• 生物源: mouse
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: AG25, monoclonal
• 分子量: antigen 88 kDa
• 物種活性: mouse, human, bovine, rat
• 技術: immunoprecipitation (IP): suitable; western blot: suitable
• 同型: IgG1
• UniProt登錄號: Q05209
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 基因資訊: human ... PTPN12(5782) ; mouse ... Ptpn12(19248) ; rat ... Ptpn12(117255)

描述

一般說明

Among the post-translational modifications, phosphorylation is a vital regulatory mechanism of key proteins involved in specific pathways. Reverse phosphorylation has become recognized as the key process of regulation of gene expression, cellular proliferation, differentiation in Eukaryotes. The protein phosphatases can be divided into two main groups: protein tyrosine phosphatases (PTPs) and protein serine/threonine phosphatases (PPs) which remove phosphate from proteins/peptides containing phosphotyrosine (pTyr) or phosphoserine/phosphothreonine (pSer/pThr), respectively. Several of the PTPs are known to control the function of growth factor receptors, many of which are tyrosine kinases encoded by oncogenes. PTP PEST is a cytosolic protein tyrosine phosphatase which is ubiquitously expressed in mammalian tissues. PTP PEST is subject to regulation via phosphorylation of Ser39 by both protein kinase C and protein kinase A
Monoclonal Anti-Protein Tyrosine Phosphatase PEST recognizes PTP PEST isoforms in all mammalian species (88 kDa).

免疫原

full-length, recombinant PTP PEST.

應用

Anti-Protein Tyrosine Phosphatase PEST antibody is suitable for immunoblotting and immunoprecipitation.

外觀

Solution in phosphate buffered saline containing 0.08% sodium azide.

準備報告

Purified from tissue culture supernatant using Protein G.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable