推薦產品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
物種活性
human, rat
技術
immunohistochemistry: suitable
western blot: suitable
UniProt登錄號
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... P2RY1(5028)
rat ... P2ry1(25265)
一般說明
嘌呤能受体 P2Y1是G 蛋白偶联受体的成员。 P2Y1 基因定位于人染色体3q25.2。它存在于心脏、血管、前列腺、睾丸、卵巢和神经组织中。
免疫原
对应于大鼠或人P2Y1残基242-258的合成肽。
應用
兔内产生的抗嘌呤能受体 P2Y1抗体已用于免疫印迹（稀释度1:200）和免疫组化（稀释度1:50）。
生化／生理作用
嘌呤能受体 P2Y1 可用作细胞外 ATP 和 ADP 的受体。它对于 ADP 诱导的血小板活化、聚集和血栓形成至关重要。P2Y1还参与基于内皮细胞的核苷酸诱导松弛和钙动员。它是产生新的抗血小板化合物和抗炎策略的潜在靶标。
外觀
从1%牛血清白蛋白和0.05%叠氮化钠的磷酸盐缓冲盐水（pH 7.4）中冻干。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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Autocrine activation of P2Y1 receptors couples Ca (2+) influx to Ca (2+) release in human pancreatic beta cells.
Khan S, Yan-Do R, Duong E, et al.
Diabetologia, 57(12), 2535-2545 (2014)
[Fatigue fracture of bone (author's transl)].
J Sebek et al.
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 43(4), 364-366 (1976-08-01)
Shara Khan et al.
Diabetologia, 57(12), 2535-2545 (2014-09-12)
There is evidence that ATP acts as an autocrine signal in beta cells but the receptors and pathways involved are incompletely understood. Here we investigate the receptor subtype(s) and mechanism(s) mediating the effects of ATP on human beta cells. We
F R Seiler et al.
Developments in biological standardization, 44, 153-163 (1979-01-01)
Unspecifically induced activation of Complement (C) in solution can be caused either by denatured Ig molecules and by polymeric aggregates of same or more specifically by antigen-antibody complexes. As a quality criteria, e.g. for i.v.-IgG preparations, it is agreed by
Milka Koupenova et al.
Frontiers in pharmacology, 9, 37-37 (2018-02-15)
Platelets are small anucleated cells present only in mammals. Platelets mediate intravascular hemostatic balance, prevent interstitial bleeding, and have a major role in thrombosis. Activation of platelet purinergic receptors is instrumental in initiation of hemostasis and formation of the hemostatic
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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