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Key Documents

P4651

Sigma-Aldrich

异丙嗪 盐酸盐

同義詞:

10-(2-二甲基氨基-1-丙基)吩噻嗪 盐酸盐

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About This Item

經驗公式(希爾表示法):
C17H20N2S · HCl
CAS號碼:
分子量::
320.88
Beilstein:
4166397
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

形狀

powder

品質等級

起源

Wyeth

儲存溫度

2-8°C

SMILES 字串

Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C

InChI

1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H

InChI 密鑰

XXPDBLUZJRXNNZ-UHFFFAOYSA-N

基因資訊

human ... HRH1(3269)

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生化/生理作用

H 1 组胺受体拮抗剂;CNS 抑制剂;抗胆碱能药。

特點和優勢

该化合物由 Wyeth 开发 。要浏览其他制药公司开发的化合物列表批准的药物/候选药物的列表, 点击这里

其他說明

溶解度:易溶于水、热无水乙醇和氯仿。几乎不溶于乙醚、丙酮和乙酸乙酯。

外觀

外观:白色或淡黄色,无味,结晶性粉末,缓慢氧化,长期暴露于空气中,呈蓝色。

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

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A B Wright et al.
Ultrasound in medicine & biology, 25(2), 241-247 (1999-05-13)
This sonographic study was aimed at examining the effect of sedation with promethazine (1.5 mg x kg(-1)), on gastroduodenal function in neonatal piglets. On 3 consecutive days, observations of gastroduodenal motility during the first 3 postprandial h were made in
Z Li et al.
Neuroscience, 70(1), 145-158 (1996-01-01)
Ionic mechanisms responsible for histamine-induced prolonged depolarization in supraoptic nucleus neurons were investigated using whole-cell patch recordings in horizontally prepared brain slices from adult male rats. Bath application of histamine (1-10 microM) in control medium induced membrane depolarization in nine
Frank Fasbender et al.
Archives of toxicology, 94(2), 439-448 (2020-02-16)
Drug-induced liver injury (DILI) represents one of the major causes why drugs have to be withdrawn from the market. In this study, we describe a new interaction between drug-exposed hepatocytes and natural killer (NK) cells. In a previous genome-wide expression
Louis C Leung et al.
Nature, 571(7764), 198-204 (2019-07-12)
Slow-wave sleep and rapid eye movement (or paradoxical) sleep have been found in mammals, birds and lizards, but it is unclear whether these neuronal signatures are found in non-amniotic vertebrates. Here we develop non-invasive fluorescence-based polysomnography for zebrafish, and show-using unbiased, brain-wide
William C Kwan et al.
The Journal of comparative neurology, 527(3), 558-576 (2018-01-03)
The primate visual brain possesses a myriad of pathways, whereby visual information originating at the retina is transmitted to multiple subcortical areas in parallel, before being relayed onto the visual cortex. The dominant retinogeniculostriate pathway has been an area of

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