P1620

Anti-PRMT1 antibody, Mouse monoclonal

clone PRMT1-171, purified from hybridoma cell culture

• 同義詞: Anti-Protein-Arginine Methyl Transferase 1
• MDL號碼: MFCD04975120
• 分類程式碼代碼: 12352203
• NACRES: NA.43
• 無性繁殖: PRMT1-171, monoclonal
• application: ELISA (i); IP; WB
• 物種活性: mouse, chicken, bovine, human, canine, hamster, monkey, rat
• 技術: immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: 2 μg/mL using whole cell extract of 293T cells
• citations: 9

屬性

• 生物源: mouse
• 品質等級: 200
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: PRMT1-171, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~42 kDa
• 物種活性: mouse, chicken, bovine, human, canine, hamster, monkey, rat
• 濃度: ~2 mg/mL
• 技術: immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: 2 μg/mL using whole cell extract of 293T cells
• 同型: IgG1
• UniProt登錄號: Q99873
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... PRMT1(3276)

描述

一般說明

Protein arginine methyltransferase 1 (PRMT1) gene is localized on human chromosome 19q13.33. It is part of the type I PRMT family.

特異性

Does not cross-react with PRMT2, 3, 4, and 5.

免疫原

full length PRMT1. Does not cross-react with PRMT2, 3, 4, and 5.

應用

Anti-PRMT1 antibody, Mouse monoclonal has been used for Immunofluorescence and Western Blotting.

生化／生理作用

Protein arginine methyltransferase 1 (PRMT1) is crucial for the formation of asymmetric dimethylarginine. It can methylate Twist-1, a transcription factor. The protein also methylates histones and thus modulates transcription and protein activity. PRMT1 is involved in epithelial-mesenchymal transition and may have a role in cancer.

外觀

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

儲存和穩定性

For continuous use, store at 2-8 C for up to one month. For prolonged storage, freeze in working aliquots at 20 C. Repeated freezing and thawing, or storage in frost-free freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable