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Merck
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文件

O9265

Sigma-Aldrich

蛇床子素

同義詞:

7-甲氧基-8-异戊烯基香豆素, 7-甲氧基-8-（3-甲基-2-丁烯基）香豆素, 蛇床子素

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About This Item

經驗公式（希爾表示法）:
C15H16O3
CAS號碼:
484-12-8
分子量：:
244.29
MDL號碼:
MFCD00076049
分類程式碼代碼:
12352205
PubChem物質ID:
329818938
NACRES:
NA.25

化驗

≥95% (HPLC)

形狀

powder

顏色

white

溶解度

methanol: soluble 10 mg/mL, clear, colorless

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

room temp

SMILES 字串

COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C

InChI

1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

InChI 密鑰

MBRLOUHOWLUMFF-UHFFFAOYSA-N

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相關類別

生化／生理作用

传统中药 蛇床子的有效成分，具有抗炎、镇痛、降脂等作用。在鹌鹑模型中显著降低脂质蓄积。它对MPP（+）诱导的PC12细胞中细胞毒性的神经保护作用支持使用蛇床子素作为治疗神经退行性疾病的治疗剂。在 HER2 过度表达的乳腺癌细胞中抑制脂肪酸合成酶的表达表明蛇床子素有望成为化疗药物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Yue-fei Zhou et al.
The Journal of surgical research, 185(2), 805-814 (2013-08-01)
Osthole, the main bioactive compounds isolated from the traditional Chinese medical herb broad Cnidium monnieri (L.) cusson, has been shown to exert spectrum of pharmacologic activities. The aim of this study was to investigate the potential neuroprotective effects of osthole
Wonhyoung Park et al.
Nutrients, 11(11) (2019-11-17)
Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer death in women. Although, recently, the number of pathological studies of breast cancer have increased, it is necessary to identify a novel compound that targets
Ola D Alabi et al.
Life sciences, 102(2), 105-110 (2014-03-25)
Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines
Natalia K Kordulewska et al.
Nutrients, 13(1) (2021-01-06)
Lipopolysaccharydes (LPS) are responsible for the intestinal inflammatory reaction, as they may disrupt tight junctions and induce cytokines (CKs) secretion. Osthole has a wide spectrum of pharmacological effects, thus its anti-inflammatory potential in the LPS-treated Caco-2 cell line as well
Jian Zhou et al.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 35(5), 561-566 (2013-11-05)
To investigate the effect of osthole on bone metabolism in rat femoral tissues in vitro. The rat femoral tissues were isolated in vitro. The optimal concentrations of ostehole (1×10(-5) mol/L) and estradiol (1×10(-8) mol/L) (the positive control) were selected by

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