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Merck
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重要文件

O1257

Sigma-Aldrich

油酸-水溶性

powder, BioReagent, suitable for cell culture

同義詞:

油酸-环糊精复合物

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About This Item

MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.75

生物源

synthetic (organic)

產品線

BioReagent

形狀

powder

成份

Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)

技術

cell culture | mammalian: suitable

溶解度

H2O: 50 mg/mL, clear to slightly hazy

儲存溫度

−20°C

SMILES 字串

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI 密鑰

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

基因資訊

應用

十八烯酸水溶液可用于:
  • 制备用于细胞处理的FFA(游离脂肪酸)混合物
  • 研究其对L6肌细胞中溶质载体家族2成员4 (SLC2A4)/GLUT4表达的影响,并用作潜在的转录调控因子
  • 制备脂肪培养基,用于诱导原代人肝细胞的体外脂肪变性

其他說明

甲基-β-环葡聚糖结合改善了油酸在培养基中的溶解度和运输。

相關產品

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Oleic and linoleic fatty acids downregulate Slc2a4/GLUT4 expression via NFKB and SREBP1 in skeletal muscle cells
Poletto A C, et al.
Molecular and Cellular Endocrinology, 401(12), 65-72 (2015)
A20 attenuates FFAs-induced lipid accumulation in nonalcoholic steatohepatitis
Ai L, et al.
International Journal of Biological Sciences, 11(12), 1436-1436 (2015)
Takashi Okumura et al.
Oncotarget, 8(11), 18280-18295 (2017-04-15)
Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and metastasis of
An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells
Boteon YL, et al.
PLoS ONE, 13(7), e0201419-e0201419 (2018)
Katerina Brychtova et al.
Bioorganic & medicinal chemistry, 18(24), 8556-8565 (2010-11-09)
Skin penetration enhancers are used in the formulation of transdermal delivery systems for drugs that are otherwise not sufficiently skin-permeable. We generated two series of esters by multi-step synthesis with substituted 6-aminohexanoic acid as potential transdermal penetration enhancers by multi-step

文章

Fatty acids of the n-3, n-6 and n-9 families are important supplements for cell culture systems. They are important in cell culture systems used to biomanufacture heterologous proteins, such as monoclonal antibodies.

Fatty acids of the n-3, n-6 and n-9 families are important supplements for cell culture systems. They are important in cell culture systems used to biomanufacture heterologous proteins, such as monoclonal antibodies.

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

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