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Key Documents

N7885

Sigma-Aldrich

神经氨酸酶 来源于霍乱弧菌

Type III, buffered aqueous solution, 0.2 μm filtered, 1-5 units/mg protein (Lowry, using NAN-lactose)

同義詞:

受体破坏酶, 唾液酸酶, 神经氨酸苷酶

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About This Item

CAS號碼:
酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

品質等級

種類

Type III

形狀

buffered aqueous solution

比活性

1-5 units/mg protein (Lowry, using NAN-lactose)

分子量

83 kDa

應用

diagnostic assay manufacturing

異物活動

Protease and NAN-aldolase, present

儲存溫度

2-8°C

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相關類別

一般說明

神经氨酸酶是糖苷水解酶,催化末端唾液酸残基的水解。最知名的莫过于促进流感病毒释放的病毒近酰胺酶。

應用

来自霍乱弧菌的神经氨酸苷酶已在一项研究中使用,以评估其在易感细胞结合和摄取霍乱毒素中的作用。它还已在另一项研究中使用,以研究钠底物的制备及其在神经氨酸酶荧光测定中的应用。
神经氨酸酶被用作糖缀合物分布和底物特异性研究的细胞表面探针。

生化/生理作用

霍乱弧菌神经氨酸酶已被证明通过结合霍乱毒素并帮助其被细胞摄取来促进霍乱毒素感染。

品質

不含防腐剂。

單位定義

除非另有说明,否则在37 °条件下,当pH为5.0时,使用NAN-乳糖或牛颌下粘蛋白,一个单位每分钟将释放1.0 μ摩尔的N-乙酰神经氨酸。价格基于将NAN-乳糖用作底物的单位。

外觀

水溶液,pH 5.5,含0.15 M NaCl和4 mM CaCl2

準備報告

色谱纯化产品。

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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