生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
mouse, rat, human
技術
western blot: 1:500-1:1,000
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... RASSF5(83593)
mouse ... Rassf5(54354)
rat ... Rassf5(54355)
一般說明
Ras association domain family member 5 (RASSF5) is also known as novel Ras effector- 1 (NORE-1). It exists in three isoforms and the gene encoding it is located on human chromosome 1q32.1.
免疫原
peptide corresponding to the NORE1 protein (amino acids 313-329). This sequence is located in the RA domain of NORE1 and is 100% conserved between human, mouse, rat, and hamster.
生化／生理作用
Ras association domain family member 5 (RASSF5) is a tumor suppressor protein. It interacts with kinases like mammalian sterile 20-like kinase 1/2 (MST1/2). RASSF5 is involved in the regulation of cell cycle and apoptosis.
外觀
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Hye Jin Kim et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 7), 813-815 (2012-07-04)
NORE1 is an important tumour suppressor in human cancers that interacts with the pro-apoptotic protein kinase MST1/2 through SARAH domains. The SARAH domain (residues 366-413) of human NORE1 was expressed in Escherichia coli, purified and crystallized using the hanging-drop vapour-diffusion
Xu-Hui Zhou et al.
Oncology reports, 32(4), 1505-1512 (2014-08-12)
Ras association (RalGDS/AF-6) domain family member RASSF5 has been implicated in a variety of key biological processes, including cell proliferation, cell cycle regulation and apoptosis. It is believed to play an important role in tumorigenesis as a tumor suppressor in
Xiaoli Liu et al.
Frontiers in oncology, 10, 600927-600927 (2021-01-26)
The principal issue derived from thyroid cancer is its high propensity to metastasize to the lymph node. Aberrant exprssion of long non-coding RNAs have been extensively reported to be significantly correlated with lymphatic metastasis of thyroid cancer. However, the clinical
Wei Guo et al.
Clinical & experimental metastasis, 32(1), 83-98 (2015-01-13)
As a result of alternative splicing and differential promoter usage, RASSF5 exists in at least three isoforms (RASSF5A-RASSF5C), which may play different roles in tumorigenesis. The present study was to detect the role of RASSF5A, B and C in esophageal
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