N4396

Nalbuphine hydrochloride hydrate

≥98% (HPLC), powder, μ and κ opioid receptors agonist

• 同義詞: 17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride hydrate
• 經驗公式（希爾表示法）: C₂₁H₂₇NO₄ · HCl · xH₂O
• CAS號碼: 23277-43-2
• 分子量：: 393.90 (anhydrous basis)
• EC號碼: 245-549-9
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24278052
• NACRES: NA.77

屬性

• product name: Nalbuphine hydrochloride hydrate, ≥98% (HPLC)
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 藥物控制: regulated under CDSA - not available from Sigma-Aldrich Canada
• 溶解度: H₂O: soluble; ethanol: soluble
• 起源: Abbott
• SMILES 字串: Cl[H].[H]O[H].[H][C@@]12Oc3c(O)ccc4C[C@H]5N(CC[C@@]1(c34)[C@@]5(O)CC[C@@H]2O)CC6CCC6
• InChI: 1S/C21H27NO4.ClH.H2O/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H;1H2/t15-,16+,19-,20-,21+;;/m0../s1
• InChI 密鑰: IUGXDRGXUYNFHK-XSFMULHUSA-N
• 基因資訊: human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988)

描述

一般說明

Nalbuphine functions as an analgesic. It has anti catabolic properties. Nalbuphine maybe associated with sedation, nausea and vomiting.

生化／生理作用

Partial agonist for μ and κ opioid receptors.

特點和優勢

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H300 + H310 + H330
• 防範說明: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• 危險分類: Acute Tox. 2 Oral
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges