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About This Item
經驗公式（希爾表示法）:
C10H16N4O7S
CAS號碼:
分子量：:
336.32
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.32
推薦產品
品質等級
化驗
≥97%
形狀
powder
溶解度
water: soluble 19.60-20.40 mg/mL
儲存溫度
−20°C
SMILES 字串
N[C@@H](CCC(=O)N[C@@H](CSN=O)C(=O)NCC(O)=O)C(O)=O
InChI
1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
InChI 密鑰
HYHSBSXUHZOYLX-WDSKDSINSA-N
一般說明
S-亚硝基谷胱甘肽（GSNO）是一种内源性氮氧化物，在肺和脑的细胞外液中高表达。
應用
S-亚硝基谷胱甘肽（GSNO）已用作：
- 作为反相色谱的标准品，与化学蒸汽发生和原子荧光检测器（RPC-CVGAFS）和反相色谱荧光（RPC-FD）相结合。
- 作为分光光度法和高效液相色谱（HPLC）测定的标准品。
生化／生理作用
S-亚硝基谷胱甘肽（GSNO）抑制兔骨骼肌中肌浆网结合肌酸激酶的活性，并最终减少肌浆网囊泡中 ATP 驱动的 Ca2+ 摄取。气道细胞中的 GSNO 使气道平滑肌松弛并增强气道纤毛运动。它还阻断气道上皮阿米洛利敏感的钠转运，同时刺激钙依赖性上皮细胞氯转运并诱导中性粒细胞凋亡。此外，它还具有抗菌活性。囊性纤维化（CF）气道中 GSNO 浓度低。它是NO供体，可作为平滑肌松弛剂和血管扩张剂，并且能抑制体内的血小板活化。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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