N3288

(+)-Norfenfluramine 盐酸盐

≥98% (HPLC), powder

• 同義詞: JP 92, NSC 43036, S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine 盐酸盐
• 經驗公式（希爾表示法）: C₁₀H₁₂F₃N · HCl
• CAS號碼: 37936-89-3
• 分子量：: 239.67
• MDL號碼: MFCD11045299
• 分類程式碼代碼: 12352116
• PubChem物質ID: 329818604
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 藥物控制: regulated under CDSA - not available from Sigma-Aldrich Canada
• 儲存條件: desiccated
• 顏色: white
• 溶解度: H₂O: >10 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F
• InChI: 1S/C10H12F3N.ClH/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13;/h2-4,6-7H,5,14H2,1H3;1H/t7-;/m0./s1
• InChI 密鑰: PIDLOFBRTWNFAR-FJXQXJEOSA-N

描述

生化／生理作用

(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.

Potent substrate for serotonin transporter; 5-HT_2A/2B agonist; anorectic

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves