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Key Documents

MSAB001

Sigma-Aldrich

SILuRich Anti-IL6 MAb, biotin conjugated

clone IL6-4G1, purified from hybridoma cell culture

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

mouse

品質等級

共軛

biotin conjugate

抗體表格

purified from hybridoma cell culture

抗體產品種類

primary antibodies

無性繁殖

IL6-4G1, monoclonal

形狀

buffered aqueous solution

物種活性

human

濃度

~1.0 mg/mL

技術

immunoblotting: suitable
immunoprecipitation (IP): 1-2 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells induced with IL 1β

同型

IgG1

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... IL6(3569)

相關類別

免疫原

Recombinant IL6

外觀

Solution in 0.01 M phosphate buffered saline pH 7.4 containing 15 mM sodium azide

法律資訊

SILu is a trademark of Sigma-Aldrich Co. LLC

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Tove Boström et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1021, 3-13 (2015-11-14)
For protein analysis of biological samples, two major strategies are used today; mass spectrometry (MS) and antibody-based methods. Each strategy offers advantages and drawbacks. However, combining the two using an immunoenrichment step with MS analysis brings together the benefits of
Ailan Guo et al.
Molecular & cellular proteomics : MCP, 13(1), 372-387 (2013-10-17)
Protein methylation is a common posttranslational modification that mostly occurs on arginine and lysine residues. Arginine methylation has been reported to regulate RNA processing, gene transcription, DNA damage repair, protein translocation, and signal transduction. Lysine methylation is best known to
Regine M Schoenherr et al.
Proteomics, 16(15-16), 2141-2145 (2016-04-21)
Immunoaffinity enrichment of peptides coupled to multiple reaction monitoring-mass spectrometry (immuno-MRM) enables highly specific, sensitive, and precise quantification of peptides and post-translational modifications. Major obstacles to developing a large number of immuno-MRM assays are poor availability of monoclonal antibodies (mAbs)
L M Biasucci et al.
Circulation, 94(5), 874-877 (1996-09-01)
Elevated plasma levels of C-reactive protein have been found in the majority of patients with unstable angina. The evidence of elevated levels of acute-phase proteins in unstable angina is in line with a growing body of evidence that suggests that
Peter M Voorhees et al.
British journal of haematology, 161(3), 357-366 (2013-02-26)
Interleukin-6 (IL6) plays a central role in multiple myeloma pathogenesis and confers resistance to corticosteroid-induced apoptosis. We therefore evaluated the efficacy and safety of siltuximab, an anti-IL6 monoclonal antibody, alone and in combination with dexamethasone, for patients with relapsed or

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