推薦產品
用途
sufficient for 100 fluorometric tests
應用
pharmaceutical
檢測方法
fluorometric
相關疾病
cardiovascular diseases
儲存溫度
2-8°C
一般說明
The plasma protein lecithin:cholesterol acyltransferase (LCAT) catalyzes the transfer of an acyl group from the sn2 position of phosphatidylcholine to the 3-hydroxyl group of cholesterol forming cholesteryl ester. This activity occurs on the surface of high density lipoprotein (HDL) and the cholesteryl esters formed by LCAT are incorporated into the core of HDL.
特點和優勢
- Non-enzymatic determination of cholesteryl ester formation.
- Not affected by LCAT inhibitors or other chemical compounds.
- Dilution or non-dilution type assay.
- Assay components stable for up to one year.
- Compatible with high-throughput handling systems.
適合性
Suitable for high-throughput screening, mechanism of action studies and structureactivity relationship (SAR) work of LCAT in plasma and serum
原則
The LCFC-LCAT Acyltransferase Activity Assay is a fluorometric assay useful for measuring the acyltransferase activity of LCAT in serum or plasma. The method detects changes in LCAT free cholesterol (LCFC) levels in the sample without the use of cholesterol oxidase, peroxidase, or the generation of hydrogen peroxide. Detection is not affected by iodoacetate or other LCAT inhibitors. LCAT activity results in a fluorometric (λEx = 320 nm/λEm = 405 nm) product proportional to the amount of free cholesterol present.
儲存類別代碼
10 - Combustible liquids
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Deficient cholesterol esterification in plasma of apoc2 knockout zebrafish and familial chylomicronemia patients.
PLoS ONE, 12(1), e0169939-e0169939 (2017)
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