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M4199

Sigma-Aldrich

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

lyophilized powder

同義詞:

MOG (40-54)

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About This Item

經驗公式(希爾表示法):
C84H127N27O21
CAS號碼:
分子量::
1851.08
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

rat

品質等級

化驗

≥97% (HPLC)

形狀

lyophilized powder

顏色

white

溶解度

deionized water: soluble

UniProt登錄號

儲存溫度

−20°C

基因資訊

mouse ... Mog(17441)
rat ... Mog(24558)

相關類別

Amino Acid Sequence

Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly

生化/生理作用

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

外觀

Lyophilized from 0.1% aqueous TFA.

其他說明

Lyophilized from 0.1% TFA in H2O

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Oligodendrocyte myelin glycoprotein (OMgp) in rat hippocampus is depleted by chronic ethanol consumption.
Okamoto H
Neuroscience Letters (2006)
Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice
Cecile Delarasse
Immunology (2013)

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