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Merck
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M3142

Sigma-Aldrich

哌替啶 盐酸盐

同義詞:

1-Methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride, Pethidine hydrochloride

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About This Item

經驗公式（希爾表示法）:
C15H21NO2 · HCl
CAS號碼:
50-13-5
分子量：:
283.79
EC號碼:
200-013-3
MDL號碼:
MFCD00058210
分類程式碼代碼:
41116107
PubChem物質ID:
24896799
NACRES:
NA.77

品質等級

200

藥物控制

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

起源

Sanofi Aventis

SMILES 字串

Cl[H].CCOC(=O)C1(CCN(C)CC1)c2ccccc2

InChI

1S/C15H21NO2.ClH/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13;/h4-8H,3,9-12H2,1-2H3;1H

InChI 密鑰

WCNLCIJMFAJCPX-UHFFFAOYSA-N

基因資訊

human ... OPRM1(4988)

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生化／生理作用

Phenylpiperidine analgesic; sedative; μ opioid receptor agonist with greater κ opioid receptor agonist activity than morphine.

特點和優勢

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301,H336

危險分類

Acute Tox. 3 Oral - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析證明 (COA)

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存取文件庫

Ting-Ting Zhang et al.
Ultrasound in medicine & biology, 41(9), 2391-2399 (2015-06-16)
This study aimed to evaluate the long-term outcomes after percutaneous microwave ablation (MWA) for patients with initial recurrent hepatocellular carcinoma (HCC) measuring ≤5 cm in diameter after hepatectomy. From May 2005 to December 2011, 89 patients with 116 initial recurrent
B C Yoburn et al.
Pharmacology, biochemistry, and behavior, 51(2-3), 535-539 (1995-06-01)
The effect of chronic opioid antagonist treatment on the analgesic potency of six opioid agonists was compared to changes in opioid receptor density and the selectivity of each agonist for mu (DAMGO), delta (DPDPE) and kappa (U69,593) opioid receptors. Mice
S E Abram et al.
Anesthesiology, 87(1), 127-134 (1997-07-01)
One measure of an opioid's efficacy is its ability to retain its analgesic effect as the intensity of a noxious stimulus is increased. A few studies have assessed the ability of either spinal or systemic opioids to produce analgesia using
A Alt et al.
The Journal of pharmacology and experimental therapeutics, 286(1), 282-288 (1998-07-10)
The ability of endogenous opioids to activate G proteins was measured in membranes from C6 rat glioma cells stably expressing a cloned rat mu receptor. Peptides representing each of the three known families of endogenous opioids (enkephalins, endorphins and dynorphins)
Vanessa S Sakalidis et al.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 8(1), 79-85 (2012-08-01)
The impact of cesarean section (CS) birth and pethidine for post-CS epidural analgesia on early breastfeeding behavior is unclear. This study aimed to measure infant sucking and breastfeeding behavior in infants of mothers who delivered by CS (CS group) and
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