全部照片(1)
About This Item
經驗公式（希爾表示法）:
C11H16N5O7PS · xC6H15N × yH2O
CAS號碼:
分子量：:
393.31 (anhydrous free acid basis)
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
NACRES:
NA.51
推薦產品
化驗
≥98% (HPLC)
形狀
solid
儲存條件
desiccated
顏色
white
溶解度
H2O: 20 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
O.CCN(CC)CC.CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1
InChI
1S/C11H16N5O7PS.C6H15N.H2O/c1-25-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(23-10)2-22-24(19,20)21;1-4-7(5-2)6-3;/h3-4,6-7,10,17-18H,2H2,1H3,(H2,12,14,15)(H2,19,20,21);4-6H2,1-3H3;1H2/t4-,6-,7-,10-;;/m1../s1
InChI 密鑰
YQMUWWZKFZERBT-IDIVVRGQSA-N
相關類別
應用
2-甲硫基腺嘌呤5′单磷酸三乙铵盐水合物已用于:
- 作为P2Y12 抑制剂用于研究其对高密度脂蛋白（HDL）内噬的刺激作用。
- 作为P2Y12 抑制剂用于研究其对全人血中血小板募集的作用。
生化／生理作用
2-甲硫基腺嘌呤5′-单磷酸三乙铵盐水合物(2-MeSAMP) 是一种腺苷基P2Y12拮抗剂 和ADP依赖性血小板凝集抑制剂。(1)它可能通过P2Y12/G(i)-依赖性机制抑制血小板活化。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Effects of P2Y1 receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel.
Labarthe B, Babin J, Bryckaert M, et al.
British Journal of Pharmacology, 166(1), 221-231 (2011)
J P Brammer et al.
British journal of pharmacology, 82(1), 61-72 (1984-05-01)
Palmitaldehyde acetal phosphatidic acid ( PGAP ) caused dose-dependent aggregation of human platelets resuspended in modified Tyrode medium, with a threshold concentration of 0.5-1 microM and an EC50 of 4 microM. Concentrations of PGAP which elicited biphasic irreversible aggregation concomitantly
Ben R Watson et al.
Metallomics : integrated biometal science, 8(1), 91-100 (2015-10-06)
Following platelet adhesion and primary activation at sites of vascular injury, secondary platelet activation is induced by soluble platelet agonists, such as ADP, ATP, thrombin and thromboxane. Zinc ions are also released from platelets and damaged cells and have been
S F Maloney et al.
Integrative biology : quantitative biosciences from nano to macro, 2(4), 183-192 (2010-05-18)
Determination of the patient-specific response to antiplatelet agents facilitates proper dosing for both acute and chronic prophylaxis. "Closed" systems (with or without flow) may fail to predict pharmacological potency in situations where platelets rapidly accumulate under flow conditions at a
Nagaraj Manickam et al.
British journal of haematology, 142(3), 457-465 (2008-06-10)
Sulfhydryl groups of platelet surface proteins are important in platelet aggregation. While p-chloromercuribenzene sulphonate (pCMBS) has been used in most studies on platelet surface thiols, the specific thiol-proteins that pCMBS reacts with to inhibit aggregation have not been well defined.
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務