跳轉至內容
Merck
全部照片(1)

重要文件

檢視所有文件

M0627

Sigma-Aldrich

7-甲基鸟苷

≥90%

登入查看組織和合約定價
全部照片(1)

About This Item

經驗公式（希爾表示法）:
C11H15N5O5
CAS號碼:
20244-86-4
分子量：:
297.27
Beilstein:
3713683
MDL號碼:
MFCD16661197
分類程式碼代碼:
41106305
PubChem物質ID:
24896562
NACRES:
NA.51

生物源

synthetic

品質等級

200

化驗

≥90%

形狀

powder

溶解度

water: 50 mg/mL, clear to hazy, colorless to faintly yellow

儲存溫度

2-8°C

SMILES 字串

C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13

InChI

1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1

InChI 密鑰

OGHAROSJZRTIOK-KQYNXXCUSA-N

尋找類似的產品？ 前往 產品比較指南

一般說明

7-甲基鸟苷结构也称为帽子（cap）。它位于细胞质mRNA的5′末端。

應用

7-甲基鸟苷已被用于去除pre rigor溶液、磷酸盐系统和磷标准溶液中的残留磷酸盐。

生化／生理作用

7-甲基鸟苷涉及帽依赖性mRNA翻译过程。它也与保护mRNA免于核糖核酸酶的降解有关，并介导核输出。7-甲基鸟苷还允许核糖体的募集。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
WXBD6067V
WXBD4936V
WXBD1944V
WXBD1203V
WXBC8755V

未看到正確版本？

如果您需要一個特定的版本，您可以透過批號來尋找特定憑證。

搜尋 COA

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Esther Z Chen et al.
Investigational new drugs, 32(4), 598-603 (2014-04-09)
Deranged cap-mediated translation is implicated in the genesis, maintenance and progression of many human cancers including mesothelioma. In this study, disrupting the eIF4F complex by antagonizing the eIF4E-mRNA-cap interaction is assessed as a therapy for mesothelioma. Mesothelioma cells were treated
G Hu et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(13), 7149-7154 (1999-06-23)
We have determined, by high resolution x-ray analysis, 10 structures comprising the mRNA cap-specific methyltransferase VP39 or specific mutants thereof in the presence of methylated nucleobase analogs (N1-methyladenine, N3-methyladenine, N1-methylcytosine, N3-methylcytosine) and their unmethylated counterparts, or nucleoside N7-methylguanosine. Together with
Vishnu Modur et al.
Nature communications, 9(1), 4410-4410 (2018-10-26)
The nature and role of global transcriptional deregulations in cancers are not fully understood. We report that a large proportion of cancers have widespread defects in mRNA transcription elongation (TE). Cancers with TE defects (TEdeff) display spurious transcription and defective
Nicolas Leulliot et al.
Structure (London, England : 1993), 16(1), 52-61 (2008-01-11)
Loss of N7-methylguanosine (m7G) modification is involved in the recently discovered rapid tRNA degradation pathway. In yeast, this modification is catalyzed by the heterodimeric complex composed of a catalytic subunit Trm8 and a noncatalytic subunit Trm82. We have solved the
L Montesano et al.
The Journal of biological chemistry, 263(10), 4939-4944 (1988-04-05)
Nucleoside analysis of the RNA from the small subunit of wheat germ cytoplasmic ribosomes shows 1 mol each of N7-methylguanosine and N6-methyladenosine/mol of RNA. Antibodies directed against each methylated nucleoside were used to localize these residues within the subunit by
查看所有相關論文

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務