L7670

PL405 trifluoroacetate salt

≥98% (HPLC)

• 同義詞: AcSKGPya-F-W-Nop-GGKNH2 trifluoroacetate salt
• 經驗公式（希爾表示法）: C₇₁H₈₃N₁₅O₁₄ · xC₂HF₃O₂
• CAS號碼: 1325307-54-7
• 分子量：: 1370.51 (free base basis)
• MDL號碼: MFCD20036265
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329817654
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to off-white
• 溶解度: acetonitrile: water (1:1): ≥10 mg/mL
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• SMILES 字串: OC(=O)C(F)(F)F.CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](Cc1cc2cccc3ccc4cccc1c4c23)C(=O)N[C@@H](Cc5ccccc5)C(=O)N[C@@H](Cc6c[nH]c7ccccc67)C(=O)N[C@@H](Cc8ccc(cc8)[N+]([O-])=O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(N)=O
• InChI: 1S/C71H83N15O14.C2HF3O2/c1-41(88)79-59(40-87)71(98)82-54(22-8-10-30-73)66(93)78-39-62(91)81-57(34-47-33-46-17-11-15-44-25-26-45-16-12-19-51(47)64(45)63(44)46)69(96)84-56(31-42-13-3-2-4-14-42)68(95)85-58(35-48-36-75-52-20-6-5-18-50(48)52)70(97)83-55(32-43-23-27-49(28-24-43)86(99)100)67(94)77-37-60(89)76-38-61(90)80-53(65(74)92)21-7-9-29-72;3-2(4,5)1(6)7/h2-6,11-20,23-28,33,36,53-59,75,87H,7-10,21-22,29-32,34-35,37-40,72-73H2,1H3,(H2,74,92)(H,76,89)(H,77,94)(H,78,93)(H,79,88)(H,80,90)(H,81,91)(H,82,98)(H,83,97)(H,84,96)(H,85,95);(H,6,7)/t53-,54-,55-,56-,57-,58-,59-;/m0./s1
• InChI 密鑰: NVRXYBFFJSLZOM-DMJUDXNFSA-N

描述

生化／生理作用

PL405 is a specific and high affinity endothelin converting enzyme-2 (ECE-2) fluorigenic substrate. PL405 is cleaved by ECE-2 at the Pya-F amide bond to yield the highly fluorigenic Ac-SKG-Pya.

特點和優勢

This compound is featured on the Endothelin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable