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Merck
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重要文件

L0302511

Sigma-Aldrich

ETT 激活剂

同義詞:

5-乙硫基四氮唑 溶液, 5-(乙硫基)-1 H-四唑, 5-(乙硫基)四唑溶液

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.21

種類

for DNA synthesis

品質等級

產品線

Proligo Reagents

包裝

pkg of 4 × 2.5 L L0302511-04

濃度

39-43 g/L (titration)

雜質

≤30 ppm water content (Karl Fischer)

顏色

clear

SMILES 字串

CCSc1nnn[nH]1

InChI

1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7)

InChI 密鑰

GONFBOIJNUKKST-UHFFFAOYSA-N

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一般說明

ETT activator is an activator solution containing 5-(Ethylthio)-1H-tetrazole – a powerful activator – in acetonitrile. It is mixed with phosphoramidite during the extension step in which it reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.

應用

ETT activator has been used in the fast and low-cost synthesis of photolithographic DNA microarrays.

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

35.6 °F

閃點(°C)

2 °C


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分析證明 (COA)

Lot/Batch Number

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Journal of nanobiotechnology, 14, 14-14 (2016-03-05)
DNA microarrays are a core element of modern genomics research and medical diagnostics, allowing the simple and simultaneous determination of the relative abundances of hundreds of thousands to millions of genomic DNA or RNA sequences in a sample. Photolithographic in

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