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Merck
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Key Documents

I8635

Sigma-Aldrich

Anti-Human IgG (whole molecule) antibody produced in rabbit

whole antiserum

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

共軛

unconjugated

抗體表格

whole antiserum

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

包含

15 mM sodium azide

技術

indirect ELISA: 1:60,000
quantitative precipitin assay: 2.5 mg/mL

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

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一般說明

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobin has two heavy (H) and two light (L) chains, held together by disulphide linkages. Each light chain comprises of one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal regions. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.

應用

Anti-Human IgG (whole molecule) antibody produced in rabbit has been used in enzyme linked immunosorbent assay.

生化/生理作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
IgG1 deficiency results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections, IgG3 mediates effector functions and IgG4 is associated with asymptomatic infection. IgG antibodies have enormous therapeutic potential and the Fc region is for the development of therapeutic antibody.

準備報告

delipidized

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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