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Key Documents

I8000

Sigma-Aldrich

2-碘苯甲酸

≥98% (TLC)

同義詞:

IBA

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About This Item

線性公式:
OIC6H4CO2H
CAS號碼:
分子量::
264.02
Beilstein:
1939973
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

2-碘苯甲酸,

化驗

≥98% (TLC)

形狀

powder

顏色

white to off-white

mp

230 °C (dec.) (lit.)

儲存溫度

−20°C

SMILES 字串

OC(=O)c1ccccc1[I]=O

InChI

1S/C7H5IO3/c9-7(10)5-3-1-2-4-6(5)8-11/h1-4H,(H,9,10)

InChI 密鑰

IFPHDUVGLXEIOQ-UHFFFAOYSA-N

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應用

色氨酸肽键断裂。

生化/生理作用

碘苯甲酸 (IBA) 可用于研究酶的结构和活性。IBA 用作氧化剂,氧化邻近巯基为酶内的二硫化物(半胱氨酸残基),导致其失活或构象变化。IBA 也用于裂解色氨酸肽键。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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J M Souza et al.
Archives of biochemistry and biophysics, 360(2), 187-194 (1998-12-16)
Rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was inactivated by peroxynitrite under biologically relevant conditions. The decrease of enzymatic activity followed an exponential function, and the concentration of peroxynitrite needed to inactivate 50% of 7 microM GAPDH (IC50) was 17 microM. Hydroxyl
T Kleinschmidt et al.
Biological chemistry Hoppe-Seyler, 370(8), 839-845 (1989-08-01)
The monomeric hemoglobin fractions of Chironomus thummi thummi (CTT) and Chironomus thummi piger (CTP) differ in the ratio of their components. The determination of the primary structure of the component CTP III was achieved by automatic Edman degradation of the
S Stoeva et al.
Biochemistry, 29(2), 527-534 (1990-01-16)
The amino acid sequence of the neutral zinc protease from Bacillus mesentericus strain 76 (MCP 76) has been determined by using peptides derived from digests with trypsin, chymotrypsin, and cyanogen bromide and from cleavage with o-iodosobenzoic acid. The peptides were
R J Duhé et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(1), 126-131 (1998-02-21)
The activation of Janus kinases (JAKs) is crucial for propagation of the proliferative response initiated by many cytokines. The proliferation of various cell lines, particularly those of hematopoietic origin, is also modulated by mediators of oxidative stress such as nitric
D Beale
The International journal of biochemistry, 21(5), 549-554 (1989-01-01)
1. Tryptic cleavage sites in bovine secretory component (SC) which become inaccessible when SC is bound to IgA dimer remained inaccessible at 60 degrees C and in 4 M urea at 37 degrees C. 2. This suggests the presence of

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