推薦產品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
GG-6, monoclonal
包含
15 mM sodium azide
技術
indirect ELISA: 1:20,000
同型
IgG1
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
一般說明
人IgG是糖蛋白抗体,含有两条相等的轻链和一对相同的重链。IgG具有四种不同亚型,范围从IgG1到IgG4。单克隆抗人IgG(Fab特异性)抗体对人IgG的Fab片段具有特异性。该抗体不与人IgG的Fc部分反应。
单克隆抗-人IgG(Fab特异性)(小鼠 IgG1 亚型)来源于小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生的杂交瘤。在血液中发现免疫球蛋白G(IgG)。它存在于人血清中,由B细胞分泌。与其他免疫球蛋白相比,IgG的血清半衰期最长。IgG的重链和轻链通过二硫键相互连接。
特異性
单克隆抗人IgG(Fab特异性)对人IgG具有免疫特异性。抗体与IgG的Fab片段反应。
免疫原
纯化的人IgG
應用
小鼠抗人IgG(Fab特异性)单克隆抗体可用于酶联免疫吸附试验(ELISA)。
生化/生理作用
母体IgG通过胎盘到达胎儿,并赋予新生儿抵抗感染的免疫防御能力。IgG与抗体依赖性细胞介导的细胞毒性(ADCC)有关,还使病毒颗粒和毒素无效。IgG的木瓜蛋白酶消化产生抗原结合片段(Fab)。IgG的胃蛋白酶消化产生可结晶片段(fc)片段和单个二聚体F(ab)2。
这些抗体可调节机体对过敏和病原性感染的免疫反应。IgG还与补体结合和自身免疫疾病有关。
外觀
本品为以腹水形式提供,并含有0.1%叠氮化钠(参见MSDS)作为防腐剂。
儲存和穩定性
若需连续使用,可在0-5℃下保存。若需延长储存时间,可将溶液以工作等分试样冷冻。不建议反复冻融。不建议无霜储存。如果长期储存后发生轻微浑浊,请在使用前通过离心澄清。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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