推薦產品
生物源
mouse
品質等級
重組細胞
expressed in E. coli
化驗
≥98% (SDS-PAGE)
形狀
lyophilized powder
效力
0.01-0.1 ng/mL ED50/EC50
品質
endotoxin tested
分子量
15.1 kDa
包裝
pkg of 10 and 50 μg
技術
cell culture | mammalian: suitable
雜質
≤1.000 EU/μg
顏色
white to yellow
UniProt登錄號
儲存溫度
−20°C
基因資訊
mouse ... Il3(16187)
相關類別
一般說明
白介素3是一种造血生长因子,可刺激嗜碱性粒细胞的发育并触发组胺、IL-4和IL-6的释放。它改善单核细胞和巨噬细胞的活化和吞噬作用,增强嗜酸性粒细胞的分泌功能。白介素3促进内皮细胞增殖和迁移。
應用
来自小鼠的白介素3已被用于确定5-脂肪氧合酶产物白细胞三烯C4(LTC4)的形成。它还被用作RPMI 1640细胞转染培养基的成分。
生化/生理作用
白细胞介素-3 (IL-3) 是一种多功能蛋白,最初称为集落形成单位刺激活性 (CFU-SA),由活化的 T 淋巴细胞产生。IL-3 在多能造血祖细胞的早期发育过程中支持多系集落的形成。IL-3 可诱导琼脂悬浮的骨髓细胞形成巨噬细胞、中性粒细胞、肥大细胞和巨核细胞。IL-3 还与 IL-2 相互作用以刺激 T 淋巴细胞的生长并诱导活化 B 细胞分泌 IgG。IL-3 的其他同义词包括全特异性血细胞生成素、多集落刺激因子、肥大细胞生长因子、爆发性促进活性、产生组胺的细胞刺激因子、P 细胞刺激因子和 WEHI-3 因子。
外觀
用 0.5 mg 牛血清白蛋白冻干。无菌过滤通过 0.2μm 型过滤器。
分析報告
通过剂量依赖性刺激小鼠 M-NFS-60 细胞增殖测定生物活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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