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Merck
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重要文件

I2282

Sigma-Aldrich

Anti-Insulin-Like Growth Factor-II antibody produced in goat

affinity isolated antibody, lyophilized powder

同義詞:

Anti-IGF-II

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About This Item

MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.41
共軛:
unconjugated
application:
ELISA (i)
Neutral
WB
無性繁殖:
polyclonal
物種活性:
mouse
citations:
1
技術:
indirect ELISA: 0.5-1.0 μg/mL
neutralization: suitable
western blot: 0.1-0.2 μg/mL

生物源

goat

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

mouse

技術

indirect ELISA: 0.5-1.0 μg/mL
neutralization: suitable
western blot: 0.1-0.2 μg/mL

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Igf2(16002)

一般說明

Insulin-like growth factor II (IGF II) also refers as multiplication stimulating activity or MSA is a protein that is structurally similar to proinsulin. It is a potent mitogen for many cultured cells like mouse 3T3 cells, normal rat kidney cells, human or chicken fibroblasts and MCF-7 human breast carcinoma cells. IGF II possess mitogenic growth factor property and hence facilitates growth-promoting activity in embryonic development. Anti-Insulin-Like Growth Factor-II antibody can be used for neutralization assays. Goat anti-Insulin-Like Growth Factor-II antibody reacts specifically with recombinant mouse IGF-II. The product has also shown 25% (approx.) cross-reactivity with recombinant human IGF-II.

免疫原

purified recombinant mouse insulin-like growth factor II, expressed in E. coli.

應用

Anti-Insulin-Like Growth Factor-II antibody can be used in ELISA and western blotting.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Qing Qiu et al.
Endocrinology, 148(10), 4803-4811 (2007-07-14)
The process of posttranslational modifications of IGF-II likely has important physiological consequences. In addition to mature IGF-II, glycosylated proIGF-II(156-amino acid peptide) and two glycosylated big IGF-II forms, IGF-II(1-104) and IGF-II(1-87), have been identified in the human circulation. Due to lack
K P Karey et al.
Cancer research, 48(14), 4083-4092 (1988-07-15)
A completely serum-free assay method has been used to compare the mitogenic activities of polypeptide growth factors and estrogens with MCF-7 and T47D human breast cancer cells in culture. The lines were maintained in a viable, slowly dividing condition in

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