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Merck
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重要文件

I1786

Sigma-Aldrich

ID-8

≥98% (HPLC)

同義詞:

1-(4-甲氧苯基)-2-甲基-3-硝基-1H-吲哚-6-醇

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About This Item

經驗公式(希爾表示法):
C16H14N2O4
CAS號碼:
分子量::
298.29
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

yellow

溶解度

DMSO: ≥10 mg/mL

儲存溫度

2-8°C

SMILES 字串

COc1ccc(cc1)-n2c(C)c([N+]([O-])=O)c3ccc(O)cc23

InChI

1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3

InChI 密鑰

VVZNWYXIOADGSW-UHFFFAOYSA-N

一般說明

ID-8 是双特异性酪氨酸磷酸化调节激酶 1A (DYRK1A) 的抑制剂。

生化/生理作用

ID-8 在体外维持小鼠胚胎干细胞 (ESC) 的自我更新和多潜能性。以稳定的速度刺激增殖(在添加 10 μg/ml 的无血清培养基中观察到)M 为期 30 天)。
在体外维持小鼠胚胎干细胞 (ESC) 的自我更新和多能性。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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