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Key Documents

HPA030086

Sigma-Aldrich

Anti-RAB11FIP3 antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

同義詞:

Anti-Eferin, Anti-KIAA0665, Anti-RAB11 family interacting protein 3 (class II), Anti-Rab11-FIP3

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About This Item

分類程式碼代碼:
12352203
人類蛋白質圖譜編號:

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

產品線

Prestige Antibodies® Powered by Atlas Antibodies

形狀

buffered aqueous glycerol solution

物種活性

human

技術

immunohistochemistry: 1:500- 1:1000

免疫原序列

QVKDLTKYLDPSGLGVISFEDFYQGITAIRNGDPDGQCYGGVASAQDEEPLACPDEFDDFVTYEANEVTDSAYMGSESTYSECETF

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

一般說明

RAB11FIP3 (RAB11 family interacting protein 3) is also termed as arfophilin and eferin. It is a Rab11 and ADP-ribosylation factor (ARF) binding protein. The RAB11FIP3 gene is located on human chromosome 16p13.3.

免疫原

RAB11 family interacting protein 3 (class II) recombinant protein epitope signature tag (PrEST)

應用

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.

生化/生理作用

RAB11FIP3 (RAB11 family interacting protein 3) participates in trafficking events like migrating endosomally-derived membranes to the cleavage furrow during cytokinesis. It helps to maintain the structural integrity of the endosomal recycling compartment. RAB11FIP3 modulates cytokinesis.

特點和優勢

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

聯結

Corresponding Antigen APREST77868

外觀

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

法律資訊

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Rab11?FIP3 is critical for the structural integrity of the endosomal recycling compartment.
Horgan CP, et al.
Traffic, 8(4), 414-430 (2007)
The iron-sulfur cluster assembly network component NARFL is a key element in the cellular defense against oxidative stress.
Corbin MV, et al.
Free Radical Biology & Medicine, 89, 863-872 (2015)
Molecular characterization of Rab11-FIP3 binding to ARF GTPases.
Schonteich E, et al.
European Journal of Cell Biology, 86(8), 417-431 (2007)
Rab11-FIP3 localises to a Rab11-positive pericentrosomal compartment during interphase and to the cleavage furrow during cytokinesis.
Horgan CP, et al.
Biochemical and Biophysical Research Communications, 319(1), 83-94 (2004)

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