全部照片(1)
About This Item
經驗公式(希爾表示法):
C14H11Cl2NO3
CAS號碼:
分子量::
312.15
Beilstein:
4198042
MDL號碼:
分類程式碼代碼:
12161501
PubChem物質ID:
NACRES:
NA.47
推薦產品
一般說明
4′-羟基双氯芬酸是一种重要的醋氯芬酸代谢物,主要存在于大鼠中。它是尿液中的重要氧化代谢物。
双氯芬酸的 CYP2C9 代谢物。
應用
4′-羟基双氯芬酸已被用于考察龙胆苦甙 (GE) 对人细胞色素P450酶的体外作用。它还被用作酶标记物,用于研究其在不同体外肝脏模型中的代谢活性。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
客戶也查看了
Metabolism of Drugs and Other Xenobiotics (2012)
Metabolic profiling of human long-term liver models and hepatic clearance predictions from in vitro data using nonlinear mixed-effects modeling
Kratochwil NA, et al.
The AAPS Journal, 19(2), 534-550 (2017)
In vitro inhibition and induction of human liver cytochrome P450 enzymes by gentiopicroside: potent effect on CYP2A6
Deng Y, et al.
Drug Metabolism and Pharmacokinetics (2013)
Lu Liu et al.
Pharmaceutical biology, 55(1), 1868-1874 (2017-06-16)
Dihydromyricetin (DHM) is the most abundant and active flavonoid component isolated from Ampelopsis grossedentata (Hand-Mazz) W.T. Wang (Vitaceae) and it possesses numerous pharmacological activities. However, whether DHM affects the activity of human liver cytochrome P450 (CYP) enzymes remains unclear. The
Nayara Cristina Perez de Albuquerque et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 146, 111826-111826 (2020-11-01)
Fenamiphos (FS) is a chiral organophosphate pesticide that is used to control nematodes in several crops. Enantioselective differences may be observed in FS activity, bioaccumulation, metabolism, and toxicity. Humans may be exposed to FS through occupational and chronic (food, water
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務