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Merck
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重要文件

H2769

Sigma-Aldrich

Anti-Hyperpolarization-Activated Cation Channel HCN2 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

mouse, human, rat

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot (chemiluminescent): 1:200-1:300 using rat brain tissue

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... HCN2(610)
mouse ... Hcn2(15166)
rat ... Hcn2(114244)

免疫原

synthetic peptide corresponding to amino acids 147-161 of human HCN2 (with additional N-terminal cysteine). The epitope is identical in mouse.

外觀

Lyophilized at 0.3 mg/mL from Phosphate Buffered Saline, pH 7.4, containing 1% Bovine Serum Albumin, and 0.05% Sodium Azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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A Ludwig et al.
The EMBO journal, 18(9), 2323-2329 (1999-05-06)
Cardiac pacemaking is produced by the slow diastolic depolarization phase of the action potential. The hyperpolarization-activated cation current (If) forms an important part of the pacemaker depolarization and consists of two kinetic components (fast and slow). Recently, three full-length cDNAs
Tigran P Norekian et al.
The Biological bulletin, 237(1), 36-47 (2019-08-24)
The pteropod mollusc Clione limacina is a feeding specialist, preying on shelled pteropods of the genus Limacina. Specialized prey-capture structures, called buccal cones, are hydraulically everted from within the mouth to capture the prey. Once captured, the prey is manipulated
B Santoro et al.
Cell, 93(5), 717-729 (1998-06-18)
The generation of pacemaker activity in heart and brain is mediated by hyperpolarization-activated cation channels that are directly regulated by cyclic nucleotides. We previously cloned a novel member of the voltage-gated K channel family from mouse brain (mBCNG-1) that contained

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