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H1635

Sigma-Aldrich

马尿酰-组氨酰-亮氨酸 水合物

chromogenic, ≥98% (HPLC), powder

同義詞:

N-Benzoyl-Gly-His-Leu, N-马尿酰-L-组氨酰-L-亮氨酸 水合物

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About This Item

經驗公式（希爾表示法）:
C21H27N5O5 · xH2O
CAS號碼:
207386-83-2
分子量：:
429.47 (anhydrous basis)
Beilstein:
5664178
EC號碼:
250-597-9
MDL號碼:
MFCD00149318
分類程式碼代碼:
12352204
PubChem物質ID:
24895469
NACRES:
NA.32

產品名稱

马尿酰-组氨酰-亮氨酸 水合物, powder, ≥98% (HPLC)

品質等級

200

化驗

≥98% (HPLC)

形狀

powder

顏色

white to off-white

溶解度

acetic acid: ~50 mg/mL

儲存溫度

−20°C

SMILES 字串

O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O

InChI

1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1

InChI 密鑰

NWOJMNXIJBZMPK-QJHJCNPRSA-N

基因資訊

human ... ACE(1636) , ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421) , ACE2(70008) , ACE3(498012)

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相關類別

Amino Acid Sequence

NBz-Gly-His-Leu

應用

N-马尿酰组氨酰亮氨酸水合物可用于对牡蛎水解产物、半膜肌样品和兔肺丙酮粉末进行血管紧张素转换酶(ACE)的抑制性检测。

生化／生理作用

N-马尿酰组氨酰亮氨酸水合物(HHL)可用作血管紧张素转换酶(ACE)的人造底物。

基底

血管紧张素转换酶底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

Lot/Batch Number
SLCG7087
SLBW5368
SLBR2049V
SLBK2049V
118K5006V

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N Nahariah et al.
Asian-Australasian journal of animal sciences, 28(6), 855-861 (2015-02-27)
Lactobacillus plantarum is used for fermentation of fish products, meat and milk. However, the utilization of these bacteria in egg processing has not been done. This study was designed to evaluate the potential of fermented egg albumen as a functional
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged
A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
Flávia Giacometti Cavalheiro et al.
Food chemistry, 333, 127482-127482 (2020-07-14)
In order to evaluate differences in the peptide profile and bioactive potential in dairy products, by increasing the protein content and using proteolytic bacteria strain to enable the release of bioactive peptides, a high-protein yogurt with adjunct culture was developed.
Anna Iwaniak et al.
International journal of molecular sciences, 22(6) (2021-04-04)
In silico and in vitro methods were used to analyze ACE- and DPP-IV-inhibiting potential of Gouda cheese with a modified content of β-casein. Firstly, the BIOPEP-UWM database was used to predict the presence of ACE and DPP-IV inhibitors in casein
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