H128

(R)(−)-α-甲基组胺 二盐酸盐

solid, ≥98% (HPLC)

• 同義詞: (R)(−)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride
• 經驗公式（希爾表示法）: C₆H₁₁N₃ · 2HCl
• CAS號碼: 75614-89-0
• 分子量：: 198.09
• MDL號碼: MFCD00083176
• 分類程式碼代碼: 12352116
• PubChem物質ID: 24277778
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: solid
• 光學活性: [α]22/D −4°, c = 0.8 in H₂O(lit.)
• 儲存條件: desiccated
• 顏色: white to off-white
• 溶解度: H₂O: soluble
• SMILES 字串: Cl.Cl.C[C@@H](N)Cc1c[nH]cn1
• InChI: 1S/C6H11N3.2ClH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m1../s1
• InChI 密鑰: IZHCNQFUWDFPCW-ZJIMSODOSA-N
• 基因資訊: human ... HRH3(11255)

描述

應用

(R)(−)-α-Methylhistamine dihydrochloride has been used as an agonist for the histamine H3 cell lines. It has also been used in the antagonist assay for the histamine H3 cell lines.

生化／生理作用

(R)(−)-α-Methylhistamine dihydrochloride is a potent, selective H₃ histamine receptor agonist which crosses the blood-brain barrier. It can inhibit histamine synthesis and release.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves