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Key Documents

H0513

Sigma-Aldrich

七(2,6-二-O-甲基)-β-环糊精

同義詞:

DM-β-CD, DM‐β‐CyD, 七-(2,6-O-二甲基)-β-环糊精, 2,6-二-O-甲基-β-环糊精, 二甲基 β-环糊精

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About This Item

經驗公式(希爾表示法):
C56H98O35
CAS號碼:
分子量::
1331.36
Beilstein:
1679144
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

生物源

synthetic

形狀

powder

SMILES 字串

COC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](OC)[C@H](O[C@@H]3COC)O[C@H]4[C@H](O)[C@@H](OC)[C@H](O[C@@H]4COC)O[C@H]5[C@H](O)[C@@H](OC)[C@H](O[C@@H]5COC)O[C@H]6[C@H](O)[C@@H](OC)[C@H](O[C@@H]6COC)O[C@H]7[C@H](O)[C@@H](OC)[C@H](O[C@@H]7COC)O[C@H]8[C@H](O)[C@@H](OC)[C@H](O[C@@H]8COC)O[C@H]1[C@H](O)[C@H]2OC

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1

InChI 密鑰

QGKBSGBYSPTPKJ-UZMKXNTCSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

七(2,6-二-O-甲基)-β-环糊精是一种亲水性环糊精衍生物,有效溶解类固醇激素、维生素A、E和K等亲脂性药物,可用于提高难溶性药物化合物的溶解度和生物利用度。

應用

七(2,6-二-O-甲基)-β-环糊精可用于:
  • 通过电子顺磁共振(EPR)光谱法测定其与各种手性氮氧化物的对映体对形成的复合物的平衡常数。
  • 通过X射线衍射(XRD)研究其与丙烯酸正丁酯和丙烯酸异冰片酯形成的复合物的晶体结构。
  • 作为手性选择剂,用于通过毛细管区带电泳法分离安非他命相关药物。

涉及的反应物:
  • 包合物的理化研究
  • 与重组膜蛋白的探测扩散和单分子相互作用
  • 与胶束的相互作用导致胶束破裂
  • 研究细胞转运,用作细胞渗透促进剂
  • 药物的理化和生物药剂学改进 ,特别是溶解和稳定性
  • 与胆固醇的相互作用

品質

杂质为过甲基化同系物,主要为六(2,6-二-O-甲基)-(2,3,6-三-O-甲基)-β-环糊精。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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