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Merck
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重要文件

GW21213

Sigma-Aldrich

Anti-KCMF1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-Hypothetical protein KCMF1, Anti-PCMF, Anti-Potassium channel modulatory factor

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

製造商/商標名

Genway 15-288-21213

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... KCMF1(56888)

免疫原

Immunogen Sequence: GI # 10047128, sequence 280-375
Recombinant potassium channel modulatory factor

應用

Anti-KCMF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

KCMF1 (DEBT91) is mapped to chromosome 2p11.2 in humans. It encodes a 381 amino acid molecule with high Ser and Thr composition and is highly conserved at its N-terminus across species. DEBT91 is suggested to be a coiled-coil nuclear phosphoprotein with zinc finger motifs at the N-terminal conserved region, which is rich in cysteine and histidine. It is an immediate early gene up-regulated during growth factor-induced branching tubulogenesis. DEBT91 plays an important role in gastric carcinogenesis. Its upregulation in response to bFGF in gastric cancer might be implicated in carcinogenesis through dysregulation of growth modulator.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Jun-Hyeog Jang
FEBS letters, 578(1-2), 21-25 (2004-12-08)
We have previously shown that fibroblast growth factor receptor 2 (FGFR2) plays an important role in gastric carcinogenesis. In this study, we have used a differential display approach to identify basic fibroblast growth factor (bFGF)-inducible genes in gastric cancer cells.
Zhixing Li et al.
Biochemical and biophysical research communications, 306(3), 623-628 (2003-06-18)
In a differential screen for genes that might be important in the regulation of epithelial morphogenesis, we identified a novel gene, Debt91 (differentially expressed in branching tubulogenesis), which is up-regulated in an in vitro model of renal tubulogenesis and branching.

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