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Merck
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重要文件

GW20030F

Sigma-Aldrich

Anti-β-2-Microglobulin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

同義詞:

Anti-B2MG

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

製造商/商標名

Genway 15-288-20030F

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... B2M(567)

免疫原

β-2-Microglobulin native protein.
Immunogen Sequence: GI # 4757826, sequence 1-119

應用

Anti-β-2-Microglobulin antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.

生化/生理作用

β-2-Microglobulin is a serum protein that forms a non-covalent association with the heavy chain of the major histocompatibility complex (MHC) class I, which is involved in the presentation of peptide antigens to the immune system. Defects in this gene can cause hypercatabolic hypoproteinemia. Amyloidosis is caused upon polymerization of intact β 2-microglobulin in patients on chronic hemodialysis.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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分析證明 (COA)

Lot/Batch Number

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P D Gorevic et al.
Proceedings of the National Academy of Sciences of the United States of America, 83(20), 7908-7912 (1986-10-01)
Systemic amyloidosis with a predilection for bone and synovium may complicate the course of patients on long-term hemodialysis. This form of amyloidosis can be typed as distinct from other amyloid diseases by using small tissue samples obtained by bone biopsy
C Bernabeu et al.
Nature, 308(5960), 642-645 (1984-04-12)
Beta 2-microglobulin (beta 2-m) is a highly conserved polypeptide (12,000 molecular weight; 12K) noncovalently associated with the heavy chain (45-48K) of the major histocompatibility complex (MHC) class I antigens. Its synthesis is required for expression of the HLA-A/B and H-2K/D
Manzoor A Wani et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(13), 5084-5089 (2006-03-22)
Two siblings, products of a consanguineous marriage, were markedly deficient in both albumin and IgG because of rapid degradation of these proteins, suggesting a lack of the neonatal Fc receptor, FcRn. FcRn is a heterodimeric receptor composed of a nonclassical

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