跳轉至內容
Merck
全部照片(1)

重要文件

G5660

Sigma-Aldrich

Lysoganglioside-GM1 from bovine brain

≥95%, lyophilized powder

登入查看組織和合約定價


About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.77

品質等級

化驗

≥95%

形狀

lyophilized powder

儲存溫度

−20°C

生化/生理作用

Suggested to be a modulator of cell growth and signal transduction. Accumulates in the nervous system of patients with GM1 gangliosidosis. Used for the preparation of GM1 derivatives containing different fatty acids, fluorescent tags, or other residues.

其他說明

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

A Kharlamov et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(14), 6303-6307 (1994-07-05)
A bilateral photochemically induced thrombotic lesion of rat sensorimotor cortex (approximately 3 mm in diameter and 25 mm3 in volume) is associated with a persistent cognition (learning and memory) deficit, which was evaluated with water maze tasks. The N-dichloroacetylsphingosine derivative
Y A Hannun et al.
Science (New York, N.Y.), 235(4789), 670-674 (1987-02-06)
Lysosphingolipids potently and reversibly inhibited protein kinase C activity and binding of phorbol dibutyrate in vitro and in human platelets. As with activation of protein kinase C by phosphatidylserine and sn-1,2-diacylglycerol, inhibition was subject to surface dilution. Accordingly, inhibition in
T Kobayashi et al.
Journal of neurochemistry, 59(4), 1452-1458 (1992-10-01)
By using a sensitive method, we assayed lysocompounds of gangliosides and asialogangliosides in tissues from four patients with GM2 gangliosidosis (one with Sandhoff disease and three with Tay-Sachs disease) and from three patients with GM1 gangliosidosis [one with infantile type
Tubaro, E., et al.
Eur. J. Pharmacol. Environ. Toxicol. Pharmacol. Soc., 248, 175-175 (1993)
R T Huang et al.
FEBS letters, 281(1-2), 39-42 (1991-04-09)
Fluorescent dansyl derivatives of 3 natural sphingolipids (gangliosides, cerebroside and sphingomyelin) were shown to be readily taken up by culture cells (HeLa-, MDCK- and primary rat brain cells). A part of the incorporated fluorescent sphingolipids remained associated with the cells

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務