F1428

氰戊菊酯

≥97%

• 同義詞: α-氰基-3-苯氧基苄基-α-(4-氯苯基)-3-甲基丁酸酯
• 經驗公式（希爾表示法）: C₂₅H₂₂ClNO₃
• CAS號碼: 51630-58-1
• 分子量：: 419.90
• Beilstein: 2025982
• MDL號碼: MFCD00055324
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329799681
• NACRES: NA.77

屬性

• 品質等級: 200
• 化驗: ≥97%
• 儲存溫度: −20°C
• SMILES 字串: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
• InChI: 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
• InChI 密鑰: NYPJDWWKZLNGGM-UHFFFAOYSA-N

描述

一般說明

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

應用

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

生化／生理作用

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

II 型拟除虫菊酯。强效钙调磷酸酶（蛋白磷酸酶 2B）抑制剂。

準備報告

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.

安全資訊

• 象形圖: GHS06,GHS09
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H335,H410
• 防範說明: P261 - P264 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable