F0287

来自人血浆的纤连蛋白蛋白水解片段

lyophilized powder, 70 kDa

• 同義詞: 纤连蛋白 溶液 来源于人类成纤维细胞
• MDL號碼: MFCD00131062
• 分類程式碼代碼: 12352202
• eCl@ss: 42020141
• NACRES: NA.75

屬性

• 生物源: human plasma
• 品質等級: 200
• 化驗: >90% (SDS-PAGE)
• 形狀: lyophilized powder
• 分子量: 70 kDa
• 包裝: pkg of 0.5 mg
• 技術: cell culture | mammalian: suitable
• 雜質: HIV and HBsAg, source material tested negative; Small proteolytic fragments, may contain traces
• 溶解度: water: soluble ≥0.500 mg/mL, clear to slightly hazy, colorless
• UniProt登錄號: P02751
• 運輸包裝: ambient
• 儲存溫度: −20°C
• 基因資訊: human ... FN1(2335)

描述

一般說明

Fibronectin 1 is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. FN1 is mapped to human chromosome 2q35. Proteolytic fragments of fibronectin has a cell binding domain.

應用

Fibronectin Proteolytic Fragment from human plasma has been used in pre adsorbed antibody blocking assay and EC-pericyte tube coassembly.

生化／生理作用

Fibronectin participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis. Proteolytic fragments of fibronectin plays a vital role in mononuclear phagocyte function.

注意

The product should be stored at -20°C.

準備報告

This product is lyophilized from phosphate buffered saline with sucrose as a cryoprotectant. The source material has tested negative for antibody to HIV, HCN, and HBsAg. It is soluble in water at 0.5 mg/mL and yields a clear to slightly hazy solution.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable