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Merck
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重要文件

EMU046441

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Gata3

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

品質等級

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GTTCCTCCGACCCCTTCTACTTGCGTTTTTCGCAGGAGCAGTATCATGAAGCCCGAAAGCGACAGATCTGTGTTTTTGAAGGCAGAAAGCAAAATGTTTGCTTCTTTTTTCAAAGGAGCTCGAGGTGGTGTCTGCATTCCAACCACTGAATCCGGATCCCATTTGTGAATAAGCCATTCAGACTCATATTCCCTATTTAACAGGGTCTCTAGTGCTGTGAAAAAAATATTGCTGAACATTGCATATAACTTATATTGTAAGAAATACTGTACATTTGAGGAAGACTTTATTGTACCTGGATAGCTGTAAGAAAGGCATGAAGGACGCCAAGAGTTTTAAGGAATATAGGGGGATTAAAGTATGGAGATACAGAAGAAACCACTAAGTCTGATGTCCAAATGGGC

Ensembl | 小鼠類登錄號

NCBI登錄號

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Jinho Lee et al.
Nucleic acids research, 42(11), 6839-6849 (2014-05-06)
Estrogen receptor alpha (ERα) expression is critical for breast cancer classification, high ERα expression being associated with better prognosis. ERα levels strongly correlate with that of GATA binding protein 3 (GATA3), a major regulator of ERα expression. However, the mechanistic
Takuya Yashiro et al.
PloS one, 10(9), e0137699-e0137699 (2015-09-12)
The transcription factor PU.1 is predominantly expressed in dendritic cells (DCs) and is essential for DC differentiation. Although there are several reports that PU.1 positively regulates the expression of DC-specific genes, whether PU.1 also has a suppressive effect on DCs

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