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Key Documents

EMU043701

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Lrpprc

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GAGCTGCTTTGCAGGAAAATGAATGTCTCCTCGCAAGTAGTACCTTTGCTCAAGCTGAAGTGAAGAATGAAGCAATAAATGGGAACTTACAGAACATTTTGTCATTTTTGGAATCGAATACATTACCTTTCTCGTTTAGTTCTTTGAGAAACAGCCTAATCCTAGGCTTCAGGAGGTCGATGAACATAGATCTTTGGAGCAAGATAACAGAATTGTTGTACAAGGATGAACGCTATTGCTCAAAGCCTCCGGGACCAGCGGAAGCTGTTGGCTATTTTCTTTATAACTTGATTGACAGCATGAGTGACTCAGAGGTACAGGCCAAGGAGGAGCGTTTGAGACAATACTTCCATCAGCTGCAGGAGATGAATGTTAAAGTTCCTGAAAACATCTACAAAGGCATTTGTAATTTGCTGAATACCTACCATGTTCCTGAATTGATTAAGGATATTAAGGTTCTGGTTGACAGAGAGAAGGTAGATTCTCAAAAAACTTCTCAAGTTACCTCATCTGATTTGGAATCAACACTTGAGAAACTCAAAGCTGAAGGCCA

Ensembl | 小鼠類登錄號

ENSMUSG00000024120

NCBI登錄號

NM_028233

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

mouse ... LRPPRC(72416) , Lrpprc(72416)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Stephany Corrêa et al.
Epigenetics, 9(8), 1172-1183 (2014-08-05)
One of the potential mechanisms of imatinib mesylate (IM) resistance in chronic myeloid leukemia (CML) is increased level of P-glycoprotein (Pgp). Pgp is an efflux pump capable of activating the multidrug resistance (MDR) phenotype. The gene encoding Pgp (ABCB1) has
Keiko Fujimoto et al.
Molecular pharmacology, 88(4), 660-675 (2015-07-17)
Tocilizumab (TCZ), a humanized anti-interleukin-6 (IL-6) receptor (IL-6R) monoclonal antibody, abrogates signal transducer protein gp130-mediated IL-6 signaling by competitively inhibiting the binding of IL-6 to the receptor, and shows clinical efficacy in autoimmune and inflammatory diseases. Despite accumulating evidence for

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