E8031

Esmolol 盐酸盐

≥98% (HPLC), solid

• 同義詞: 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride 盐酸盐
• 經驗公式（希爾表示法）: C₁₆H₂₆NClO₄
• CAS號碼: 81161-17-3
• 分子量：: 331.83
• MDL號碼: MFCD00941432
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329799075
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 儲存條件: desiccated
• mp: 89.0-90.6 °C
• 溶解度: H₂O: 12 mg/mL
• 起源: Baxter
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1
• InChI: 1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H
• InChI 密鑰: GEKNCWBANDDJJL-UHFFFAOYSA-N
• 基因資訊: human ... ADRB1(153) , ADRB2(154)

描述

應用

Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.

生化／生理作用

Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.

Esmolol hydrochloride is a ultrashort-acting β₁ adrenoceptor antagonist (β₁ receptor occupancy = 84.7%).

特點和優勢

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves