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Merck
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Key Documents

E6632

Sigma-Aldrich

环氧活化琼脂糖

lyophilized powder

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About This Item

MDL號碼:
分類程式碼代碼:
23151817
NACRES:
NA.56

形狀

lyophilized powder

品質等級

標籤範圍

≥20 μmol per mL

技術

affinity chromatography: suitable

基質

cross-linked 4% beaded agarose

基質活性組

epoxy

基質結合

through epoxy to hydroxyl

基質墊片

12 atoms

膨潤

1 g swells to ~3 mL

適合性

suitable for chromatography

儲存溫度

−20°C

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一般說明

环氧活化琼脂糖是一种树脂。配体可以通过配体的亲核基团与环氧基的交互效应与琼脂糖共价连接。
when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.

應用

环氧活化琼脂糖是用乳糖稳定的冻干粉末,用于亲和色谱法,蛋白色谱法和活化/功能化基质。环氧活化的琼脂糖已用于研究对人源性癌细胞以及癌症防治的抗增殖活性。

其他說明

配体:1,4-双(2:3-环氧丙氧基)丁烷
连接:一个环氧基
间隔基:当配体与游离环氧基偶联时,提供 12 原子间隔基。连接是一种稳定的不带电的醚。

外觀

用乳糖稳定化的冻干粉

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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S Ranganathan et al.
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G J Fennington et al.
Microbiology (Reading, England), 142 ( Pt 2), 321-330 (1996-02-01)
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Biochemical and biophysical research communications, 323(3), 743-749 (2004-09-24)
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J J Malinowski et al.
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Adel M Nour et al.
Infection and immunity, 77(3), 1262-1271 (2009-01-07)
Multiple microbial components trigger the formation of an inflammasome complex that contains pathogen-specific nucleotide oligomerization and binding domain (NOD)-like receptors (NLRs), caspase-1, and in some cases the scaffolding protein ASC. The NLR protein Nalp1b has been linked to anthrax lethal

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