生物源
goat
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
物種活性
mouse
技術
immunohistochemistry: 2-15 μg/mL using cells and tissues
indirect ELISA: 0.5-1.0 μg/mL
western blot: 0.1-0.2 μg/mL
UniProt登錄號
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
mouse ... Efnb1(13641)
一般說明
By ELISA, the antibody shows less than 1% cross-reactivity with rhEphrin-A3, rhEphrin-A4, rhEphrin-A5, and rhEphrin-B3. Also, there is less than 1% cross-reactivity with rmEphrin-A1, rmEphrin B2, rmEphrin-A2, rmEphrin-A4, and rzfEphrin-B2.
免疫原
purified recombinant mouse ephrin-B1 extracelluar domain expressed in mouse NSO cells.
應用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunofluorescence (1 paper)
生化／生理作用
Ephrin B4 binds to EPH receptor B, a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. EphB receptors and EphrinB ligands have a regulatory effect on endothelial cell function, angiogenesis, migration, cell growth and survival.
外觀
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline and 5% trehalose.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Paola D Vermeer et al.
PloS one, 7(1), e30447-e30447 (2012-01-27)
In non-cancerous cells, phosphorylated proteins exist transiently, becoming de-phosphorylated by specific phosphatases that terminate propagation of signaling pathways. In cancers, compromised phosphatase activity and/or expression occur and contribute to tumor phenotype. The non-receptor phosphatase, PTPN13, has recently been dubbed a
Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis.
Ombretta Salvucci et al.
Advances in cancer research, 114, 21-57 (2012-05-17)
Eph receptor tyrosine kinases and their Ephrin ligands represent an important signaling system with widespread roles in cell physiology and disease. Receptors and ligands in this family are anchored to the cell surface; thus Eph/Ephrin interactions mainly occur at sites
Yu-Ting Mao et al.
Neuron, 98(4), 767-782 (2018-05-08)
Dendritic filopodia select synaptic partner axons by interviewing the cell surface of potential targets, but how filopodia decipher the complex pattern of adhesive and repulsive molecular cues to find appropriate contacts is unknown. Here, we demonstrate in cortical neurons that
Paul L Colbert et al.
Oncotarget, 6(2), 953-968 (2014-12-02)
Microtubules (MTs) are components of the cytoskeleton made up of polymerized alpha and beta tubulin dimers. MT structure and function must be maintained throughout the cell cycle to ensure proper execution of mitosis and cellular homeostasis. The protein tyrosine phosphatase
eph, the largest known family of putative growth factor receptors.
N L Tuzi et al.
British journal of cancer, 69(3), 417-421 (1994-03-01)
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