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Key Documents

E1528

Sigma-Aldrich

雌激素受体-α 人

≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution

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About This Item

MDL號碼:
分類程式碼代碼:
51111800
NACRES:
NA.32

重組細胞

expressed in baculovirus infected insect cells

品質等級

化驗

≥80% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

分子量

66.4 kDa

包裝

vial of 211 pmol

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... ESR1(2099)

生化/生理作用

激素诱导型转录因子,能够对组织生长和分化相关的基因发挥正性或负性调节作用。用于信号传导、类固醇生物化学和内分泌干扰物研究。

外觀

溶于 50 mM Tris-HCl (pH 8.0)、500 mM KCl、2 mM DTT、1 mM EDTA、1 mM 原钒酸盐 和 10% 甘油中。

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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G G Kuiper et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(12), 5925-5930 (1996-06-11)
We have cloned a novel member of the nuclear receptor superfamily. The cDNA of clone 29 was isolated from a rat prostate cDNA library and it encodes a protein of 485 amino acid residues with a calculated molecular weight of
G G Kuiper et al.
Endocrinology, 138(3), 863-870 (1997-03-01)
The rat estrogen receptor (ER) exists as two subtypes, ER alpha and ER beta, which differ in the C-terminal ligand binding domain and in the N-terminal transactivation domain. In this study we investigated the messenger RNA expression of both ER
K Paech et al.
Science (New York, N.Y.), 277(5331), 1508-1510 (1997-09-05)
The transactivation properties of the two estrogen receptors, ERalpha and ERbeta, were examined with different ligands in the context of an estrogen response element and an AP1 element. ERalpha and ERbeta were shown to signal in opposite ways when complexed
S Mosselman et al.
FEBS letters, 392(1), 49-53 (1996-08-19)
A novel estrogen receptor (hereinafter referred to as ER beta) was cloned using degenerate PCR primers. A comparison of the amino acid sequence of ER beta with the "classical' ER (ER alpha) shows a high degree of conservation of the

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