E1283

ERK2，活性，GST 标记 人

recombinant, expressed in E. coli, PRECISIO^® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 同義詞: ERT1, MAPK1, MAPK2, P41mapk, P42MAPK, PRKM1, PRKM2, p40, p47
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 重組細胞: expressed in E. coli
• 品質等級: 200
• 產品線: PRECISIO^® Kinase
• 化驗: ≥70% (SDS-PAGE)
• 形狀: buffered aqueous glycerol solution
• 比活性: 613-829 nmol/min·mg
• 分子量: ~68 kDa
• UniProt登錄號: P28482
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... MAPK1(5594)

描述

生化／生理作用

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

外觀

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律資訊

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable